The Tax Cuts and Jobs Act of 2017 removed the home office deduction for most employees. For those who still qualify, Employee Business Use of Home expenses are reported on Line 4 of IRS Form 2106 Employee Business Expenses, which flows to Schedule 1 (Form 1040), Line 24.
For tax years 2018 - 2025, specific occupations can take this deduction:
To access the Q&A interview screens to enter your home office expenses: